| Negative | Uncertain | Positive | |
| "No mutation detected" or "Favor polymorphism" |
"Genetic change of uncertain significance" | "Positive for a deleterious mutation" or "Suspected deleterious" | |
| Comprehensive BRACAnalysis® | Your test found no mutations in the BRCA1 or BRCA2 genes. Your risk of hereditary breast and ovarian cancer is significantly lower than the risk of a person who tests positive for a BRCA1 or BRCA2 mutation, but please remember:
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Your test found a gene alteration, but an associated cancer risk is either not known or not confirmed. | Your test found a mutation that increases the risk of developing breast and ovarian cancer. |
| Single Site BRACAnalysis® | You do not have the specific mutation you were tested for. This test only looks for a specific mutation that runs in your family; and you still have the same risk for developing breast or ovarian cancer as the general population. Also, there are rare instances in which more than one inherited mutation runs in a family. In such cases, a negative Single Site BRACAnalysis® result only rules out one inherited mutation. | Because this test looks for known mutations only, there are no "Uncertain" results. | Your test found a mutation that increases the risk of developing breast and ovarian cancer. |
| Multisite 3 BRACAnalysis® | Your test found none of the three most common Ashkenazi mutations in the BRCA1 or BRCA2 genes. This is good news, but it is important to remember that other mutations may exist. Comprehensive BRACAnalysis® can look for other mutations in the BRCA1 and BRCA2 genes that may put you at risk. | Because this test looks for known mutations only, there are no "Uncertain" results. | Your test found a mutation that increases the risk of developing breast and ovarian cancer. |